Johns Hopkins University Trial Innovation Center (JHU TIC)

BIOS Clinical Trials Coordinating Center and the Johns Hopkins Institute for Clinical and Translational Research (ICTR) were awarded a $24.5 million grant from the National Institutes of Health’s National Center for Advancing Translational Sciences (NCATS) to continue efforts as a Trial Innovation Center (TIC).

The goal of the center is to promote innovations in the efficiency and quality of NIH-funded trials. The center is part of the NCATS Trial Innovation Network and work with the NCATS Clinical and Translational Science Awards (CTSA) Program, which funds a national consortium of medical research institutions. The center will help the institutions form a long-standing infrastructure for multicenter studies to be funded by NIH and other funding agencies.

Daniel F. Hanley, M.D., the Jeffrey and Harriet Legum Professor of Acute Neurological Medicine and director of BIOS CTCC at the Johns Hopkins University School of Medicine, is the principal investigator for the grant. Daniel Ford, M.D., M.P.H., the David M. Levine Professor and senior associate dean for clinical and translational research at the Johns Hopkins University School of Medicine, is a co-principal investigator. Karen Lane, an assistant professor of neurology at Johns Hopkins, is also a co-principal investigator. Megan Kasimatis Singleton, J.D., M.B.E., assistant dean for human research protection and director of the Office of Human Subjects Research at Johns Hopkins, coordinates single Institutional Review Board (sIRB) activities supported by the grant.

This work is a continuation of the first round of TIC grants. In 2017, BIOS Clinical Trials Coordinating Center and the Johns Hopkins Institute for Clinical and Translational Research (ICTR) were awarded a seven-year, $25 million grant from NCATS to form, along with Tufts University School of Medicine, one of three Trial Innovation Centers.